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  1. #1
    Banned Ziegler's Avatar
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    Default Darkfall Players save....AIDS cured!!!

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    A 45-year-old man now living in the Bay Area may be the first person ever cured of the deadly disease AIDS, the result of the discovery of an apparent HIV immunity gene.

    Timothy Ray Brown tested positive for HIV back in 1995, but has now entered scientific journals as the first man in world history to have that HIV virus completely eliminated from his body in what doctors call a “functional cure.”


    Brown was living in Berlin, Germany back in 2007, dealing with HIV and leukemia, when scientists there gave him a bone marrow stem cell transplant that had astounding results.

    “I quit taking my HIV medication the day that I got the transplant and haven’t had to take any sense,” said Brown, who has been dubbed “The Berlin Patient” by the medical community.

    Brown’s amazing progress continues to be monitored by doctors at San Francisco General Hospital and at the University of California at San Francisco medical center.

    “I’m cured of HIV. I had HIV but I don’t anymore,” he said, using words that many in the scientific community are cautiously clinging to.

    Sceintists said Brown received stem cells from a donor who was immune to HIV. In fact, about one percent of caucasians are immune to HIV. Some researchers think the immunity gene goes back to the Great Plague: people who survived the plague passed their immunity down and their heirs have it today.

    UCSF’s Dr. Jay Levy, who co-discovered the HIV virus and is one of the most respected AIDS researchers in the world, said this case opens the door to the field of “cure research,” which is now gaining more attention.

    “If you’re able to take the white cells from someone and manipulate them so they’re no longer infected, or infectable, no longer infectable by HIV, and those white cells become the whole immune system of that individual, you’ve got essentially a fuctional cure,” he explained.

    UCSF’s Dr. Paul Volberding, another pioneering AIDS expert who has studied the disease for all of its 30 years cautioned that while “the Berlin Patient is a fascinating story, it’s not one that can be generalized.”

    Both doctors stressed that Brown’s radical procedure may not be applicable to many other people with HIV, because of the difficulty in doing stem cell transplants, and finding the right donor.

    “You don’t want to go out and get a bone marrow transplant because transplants themselves carry a real risk of mortality,” Volberding said.

    He explained that scientists also still have many unanswered questions involving the success of Brown’s treatment.

    “One element of his treatment, and we don’t know which, allowed apparently the virus to be purged from his body,” he observed. “So its going to be an interesting, I think productive area to study.”

    Volberding continued, “Knock on wood, (Brown) hasn’t had any recurrance now for several years of the virus, and that hasn’t happened before in our experience.”

    As a result, at the San Francisco AIDS Foundation some are now using the word “cure” after so many avoided it for decades.

    “You sort of felt like you couldn’t say ‘cure’ for a number of years. Scientists and clinicians and people with HIV alike felt that was a promise that was never going to be realized and it was dangerous to direct a lot of energy toward it,” said Dr. Judy Auerbach. “And now things have shifted.”

    The California Institute of Regenerative Medicine is currently funding stem cell research in the Bay Area based on Brown’s case in the hopes of replicating his success for broader populations of people with HIV.

    The institute said it plans to begin clinical trials next year.

  2. #2
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    Well that's pretty cool.

  3. #3
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    Gene therapy isn't new. The receptor that the HIV virus uses to enter the T cells isn't news, either. This guy had luekemia. The process of using chemo to destroy stem cells and a bone marrow transplant was required. He had nothing to lose. He's a lucky man. This basically means that his body literally had no functional WBC stem cells of his own when he got the transplant. That pretty much never happens. There is always some of your own left. If he had just one functional WBC stem cell in his body, this wouldn't have happened and he wouldn't be cured.

    This isn't a very likely cure seeing how you basically have to bring yourself an inch from death using chemo and then get a genetically alter WBC stem cell transplant to cure HIV. Want to guess how much all this costs?

    Here's another fact, if people can afford current therapies and actually take them, their life expectancy is the same.
    Last edited by Falokis; 05-16-2011 at 23:22.

  4. #4
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    Quote Originally Posted by Falokis View Post
    Gene therapy isn't new. The receptor that the HIV virus uses to enter the T cells isn't news, either. This guy had luekemia. The process of using chemo to destroy stem cells and a bone marrow transplant was required. He had nothing to lose. He's a lucky man. This basically means that his body literally had no functional WBC stem cells of his own when he got the transplant. That pretty much never happens. There is always some of your own left. If he had just one functional WBC stem cell in his body, this wouldn't have happened and he wouldn't be cured.

    This isn't a very likely cure seeing how you basically have to bring yourself an inch from death using chemo and then get a genetically alter WBC stem cell transplant to cure HIV. Want to guess how much all this costs?

    Here's another fact, if people can afford current therapies and actually take them, their life expectancy is the same.
    dont matter, it's opening a path. Now that they know it can work, they can try to find a way to make it work without a transplant.

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    This=epic.

    I hope those scientist who helped cure this get at least a couple of million.

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    Old.

  7. #7
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    Quote Originally Posted by Chandrasekhar View Post
    Old.
    Quote Originally Posted by Article
    May 16, 2011 12:25 PM
    ?

  8. #8

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    Old news, whilst stem cell therapy looks promising in a number of fields the proceedure carried out on this guy isn't replicable without potentially being fatal.
    Don't hold your breath, IF they have found something by now it could be 10 years before we see it, specially with the laws regualting how and what you can do with stem cells so far (cus it's playin god ryt? fucking religious nuts)

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    Quote Originally Posted by Apex Vertigo View Post
    ?
    http://www.nytimes.com/2008/11/14/health/14hiv.html

    Published: November 13, 2008

    Doctors in Berlin are reporting that they cured a man of AIDS by giving him transplanted blood stem cells from a person naturally resistant to the virus.

    Quote Originally Posted by Reigngod View Post
    Deductive reasoning has noing to do with logic. In fact deductive reasoning is illogical. Go define logic and come back to the discussion an educated man.

  10. #10
    8000+ Long term follower Tenebrion's Avatar
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    I hear stem-cells are evil, or something like that.

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    Quote Originally Posted by Tenebrion View Post
    I hear stem-cells are evil, or something like that.
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  12. #12
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    Quote Originally Posted by Tenebrion View Post
    I hear stem-cells are evil, or something like that.
    Wait, they did this with stem cells from embryos?

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    http://www.youtube.com/watch?v=n0R48wZilZ8


    Couldn't find a better clip, but you get it.

  14. #14
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    Quote Originally Posted by Ragnarok Delrhe View Post
    dont matter, it's opening a path. Now that they know it can work, they can try to find a way to make it work without a transplant.
    Using this type of method, I don't see how that would be possible. The reason it "cured" him is because all of his WBC and bone marrow stem cells were wiped out by the chemo. That gave the virus nothing to replicate in. Then, they added new stem cells (to his bone marrow) that didn't have the receptor required for infection. This allowed his body to fight and destroy the infection. It might be possible to do it without chemo, but it's not going to be possible without a transplant using this method. It will still be pretty difficult because it's not like just anyone can take anyone's WBC stem cells. They will get rejected just like any other transplant and the new WBC might attack their new host.

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    This was kinda of old, they discovered that if you had a natural immunity to the black plague (which some people actual did by a rare gene called delta- blah blah someshit) and so they where naturally immune, but apparently hey both have the same type of infection processes where they hijack white blood cells to lymph nodes and other immune system pieces and rip them apart. Which is why if you had the black plague your lymph nodes in your throat would go explode. But apparently the gene has some sort of block on the cell that stops the virus from entering.
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