What is malediction protection?

[Finddus]

The effect on spell curse in witchcraft tree effects malediction protection (http://darkfall.wikia.com/wiki/Witchcraft) but what does that even mean?

[Melamoto]

Malediction Protection is probably defence against DoTs and Debuffs

[In Nox]

Protection against Witchcraft spells.

Every tree has this.

Fire gives protection from fire, Water from water, holy from holy, etc.

[Finddus]

Protection against Witchcraft spells.

Every tree has this.

Fire gives protection from fire, Water from water, holy from holy, etc.

I think your thinking about infernal shield/ward in the necromancy tree. This is a spell that reduces the protection of the target.